Giuseppe Biagini Selected Research

des-n-octanoyl ghrelin

3/2022	Prospective Evaluation of Ghrelin and Des-Acyl Ghrelin Plasma Levels in Children with Newly Diagnosed Epilepsy: Evidence for Reduced Ghrelin-to-Des-Acyl Ghrelin Ratio in Generalized Epilepsies.
1/2019	Decreased ghrelin and des-acyl ghrelin plasma levels in patients affected by pharmacoresistant epilepsy and maintained on the ketogenic diet.
1/2018	High plasma levels of ghrelin and des-acyl ghrelin in responders to antiepileptic drugs.
11/2011	Beneficial effects of desacyl-ghrelin, hexarelin and EP-80317 in models of status epilepticus.

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Giuseppe Biagini Research Topics

Disease

26	Seizures (Absence Seizure) 04/2022 - 10/2002
19	Status Epilepticus (Complex Partial Status Epilepticus) 04/2022 - 01/2005
16	Epilepsy (Aura) 03/2022 - 10/2002
13	Temporal Lobe Epilepsy 04/2022 - 01/2002
5	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2020 - 02/2002
4	Drug Resistant Epilepsy 04/2021 - 10/2017
2	Neuroinflammatory Diseases 11/2021 - 01/2020
2	Nervous System Diseases (Neurological Disorders) 10/2017 - 04/2010
2	Cachexia 10/2017 - 01/2014
2	Body Weight (Weight, Body) 10/2017 - 08/2002
2	Hypoxia (Hypoxemia) 08/2015 - 03/2013
2	Fibrosis (Cirrhosis) 07/2005 - 09/2002
1	Generalized Epilepsy 03/2022
1	COVID-19 04/2021
1	HIV Infections (HIV Infection) 01/2019
1	Weight Loss (Weight Reduction) 10/2017
1	Malnutrition (Nutritional Deficiencies) 10/2017
1	Neoplasms (Cancer) 10/2017
1	Pain (Aches) 01/2017
1	Gliosis 01/2016
1	Anorexia 01/2014
1	Anorexia Nervosa 01/2014
1	Starvation 01/2014
1	Hirsutism 02/2013
1	Intellectual Disability (Idiocy) 01/2013
1	Hypersensitivity (Allergy) 02/2012
1	Drug-Related Side Effects and Adverse Reactions 02/2012
1	Hyperhomocysteinemia 09/2010
1	Migraine Disorders (Migraine) 04/2010
1	Disease Progression 04/2010
1	Multiple Sclerosis 04/2010
1	Neuralgia (Stump Neuralgia) 04/2010
1	Absence Epilepsy (Childhood Absence Epilepsy) 01/2009

Drug/Important Bio-Agent (IBA)

17	Pilocarpine (Ocusert)FDA LinkGeneric 11/2021 - 01/2002
9	Anticonvulsants (Antiepileptic Drugs)IBA 02/2021 - 04/2010
8	Pregnanolone (Allopregnanolone)IBA 01/2021 - 01/2009
7	NeurosteroidsIBA 02/2021 - 10/2006
6	GhrelinIBA 03/2022 - 11/2011
5	Kainic Acid (Kainate)IBA 11/2021 - 01/2002
4	des-n-octanoyl ghrelinIBA 03/2022 - 11/2011
3	Pharmaceutical PreparationsIBA 03/2022 - 02/2012
3	Ghrelin ReceptorsIBA 01/2016 - 11/2011
3	Finasteride (Propecia)FDA LinkGeneric 02/2013 - 01/2009
3	gamma-Aminobutyric Acid (GABA)IBA 04/2010 - 10/2002
2	Triglycerides (Triacylglycerol)IBA 04/2022 - 01/2014
2	CannabidiolIBA 04/2022 - 07/2020
2	Progesterone FDA LinkGeneric 01/2020 - 10/2018
2	Cholinergic Agents (Cholinergics)IBA 11/2019 - 02/2002
2	Aminobutyrates (Aminobutyric Acid)IBA 10/2018 - 02/2013
2	hexarelinIBA 10/2017 - 11/2011
2	SecretagoguesIBA 10/2017 - 01/2013
2	Growth Hormone (Somatotropin)IBA 10/2017 - 01/2013
2	SteroidsIBA 01/2017 - 10/2006
2	pimonidazoleIBA 08/2015 - 03/2013
2	Carbamazepine (Tegretol)FDA LinkGeneric 02/2013 - 04/2010
2	Lamotrigine (Lamictal)FDA LinkGeneric 02/2013 - 04/2010
2	Diazepam (Valium)FDA LinkGeneric 01/2013 - 07/2008
2	Proteins (Proteins, Gene)FDA Link 07/2005 - 01/2005
1	PPAR gammaIBA 04/2022
1	Olive OilIBA 12/2021
1	OilsIBA 12/2021
1	CannabinoidsIBA 12/2021
1	Terpenes (Terpenoids)IBA 12/2021
1	Dronabinol (THC)FDA LinkGeneric 07/2020
1	Proline (L-Proline)FDA Link 06/2020
1	trilostane FDA Link 01/2020
1	CarbohydratesIBA 01/2019
1	JMV2894IBA 10/2017
1	Cisplatin (Platino)FDA LinkGeneric 10/2017
1	NeuropeptidesIBA 01/2017
1	2-chloro-5-nitrobenzanilideIBA 01/2017
1	CytokinesIBA 01/2016
1	AntibodiesIBA 01/2016
1	Ketone BodiesIBA 01/2014
1	Peptide Hormones (Polypeptide Hormones)IBA 01/2014
1	AdiponectinIBA 01/2014
1	Oxygen (Dioxygen)IBA 03/2013
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2013
1	macimorelinIBA 01/2013
1	Neuroprotective AgentsIBA 01/2013
1	LigandsIBA 11/2011
1	HomocysteineIBA 09/2010
1	Voltage-Gated Sodium ChannelsIBA 04/2010
1	ganaxoloneIBA 04/2010
1	Phenytoin (Dilantin)FDA LinkGeneric 04/2010
1	Lacosamide FDA Link 01/2009
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2009
1	5-alpha Reductase InhibitorsIBA 01/2009
1	GABA-B ReceptorsIBA 01/2009
1	Angiotensin IIIBA 07/2005
1	IntegrinsIBA 07/2005
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2002
1	ConvulsantsIBA 10/2002
1	delaprilIBA 09/2002
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 09/2002

Therapy/Procedure

5	Ketogenic Diet 04/2021 - 01/2014
3	Therapeutics 01/2019 - 01/2009
1	Injections 11/2019
1	Drug Therapy (Chemotherapy) 10/2017
1	High-Protein Low-Carbohydrate Diet (Atkins Diet) 01/2014